GHK-Cu (copper tripeptide-1) is one of the most extensively studied peptides in skin- and tissue-repair research. This guide covers what it is, the mechanisms researchers study, and how it is handled in the lab — for research and educational purposes only.
What is GHK-Cu?
GHK-Cu is a naturally occurring copper-binding tripeptide made of three amino acids (glycine-histidine-lysine) complexed with a copper ion. First isolated by Dr Loren Pickart in 1973, it occurs naturally in human plasma, saliva and urine — and its concentration declines with age, a fact that has driven decades of research interest.
Mechanisms studied in research
- Collagen & extracellular matrix — studied for signalling the synthesis of collagen, elastin and other matrix proteins.
- Tissue remodelling & repair — a long-standing area of wound-healing and skin-repair research.
- Antioxidant & anti-inflammatory activity — studied for modulating oxidative-stress markers.
- Gene expression — research suggests GHK-Cu influences a broad set of genes tied to tissue maintenance.
Why the copper complex matters
The copper ion is central. GHK has a high affinity for copper(II), and the GHK-Cu complex is the form most studied for delivering copper to tissues in a controlled way — which is why research material is supplied as the copper complex rather than the bare peptide.
Handling & quality
Copper peptides are sensitive to light and oxidation, so purity matters. Every Vero Labs peptide ships with an independent Certificate of Analysis and HPLC purity verification. See our reconstitution guide for correct lab handling.
Vero Labs GHK-Cu range
Third-party tested, COA-backed, shipped New Zealand-wide. More in the Research Hub.
Disclaimer: This content is for educational and research purposes only. The compound is supplied for laboratory research use only and is not for human or veterinary consumption. Nothing here is medical advice or a therapeutic claim. Not approved by Medsafe for human use.